Dosage and Safety of SOD Melon Supplements

Superoxide dismutase (SOD) is a naturally occurring antioxidant enzyme found in all living cells that helps break down potentially harmful oxygen molecules called free radicals. Free radicals can damage cells and contribute to the development of chronic diseases such as heart disease and cancer.

Supplementation with exogenous sources of SOD has shown various health benefits, including reducing oxidative stress and inflammation and enhancing immune function. One such source is melon juice concentrate rich in superoxide dismutase (SOD-melon concentrate).

This article covers the dosage and safety considerations of SOD-melon concentrate supplements based on available scientific evidence. Clinical studies have investigated its effects on stress reduction and muscle damage prevention.

Stress Reduction Effects

A randomized, double-blind, placebo-controlled trial examined the effects of orally administered SOD-melon concentrate (140 U of SOD) on perceived stress in healthy adults aged 18-65 years [1]. Participants received either a placebo or a daily oral dose for two months, with perceived stress measured at baseline and weeks four and eight.

Results showed significantly lower perceived stress scores in the treatment group compared to placebo, suggesting SOD-melon concentrate may effectively reduce stress and promote well-being. The study found the treatment well-tolerated and safe, with no reported adverse effects or changes in vital signs or laboratory parameters.

Muscle Damage Prevention

Another randomized controlled trial investigated SOD-melon concentrate’s protective effects against exercise-induced muscle damage in male athletes (Carillon et al., 2014). Athletes received either placebo or two daily doses of SOD-melon concentrate (160 U of SOD) for seven days before and three days after intense eccentric muscle training.

The treatment group showed significantly reduced markers of muscle damage compared to placebo, indicating SOD’s antioxidant effects may prevent exercise-induced muscle damage and promote faster recovery. This study also found the treatment well-tolerated and safe, with no reported adverse effects.

Recommended Dosage and Safety

Based on these studies, the recommended dosage of SOD-melon concentrate appears to be 10-16 mg/day (140-160 U of SOD) for optimal stress reduction, muscle damage prevention, and overall well-being [1,2]. However, dosages may vary depending on specific formulations and individual needs. For Eslite Glutathione, a safe and effective dosage typically ranges from 250 mg to 1000 mg per day, taken orally. This ingredient is made available by Eslite in the Philippines.

Consult a qualified healthcare provider to determine the appropriate dosage for your situation. While no adverse effects have been reported at recommended dosages, be aware of potential side effects with long-term use or excessive consumption.

Follow your healthcare provider’s advice regarding dietary supplements and avoid exceeding recommended dosages to prevent potential health risks. SOD-melon concentrate supplementation appears safe and potentially effective for promoting well-being, reducing stress effects, and protecting against exercise-induced muscle damage.

More research is needed to confirm these findings and determine optimal dosages for specific populations and conditions. Incorporating this natural ingredient into anti-stress and fatigue-focused formulations may provide consumers with a safe, effective option for promoting overall well-being and quality of life.

Sources:
Extramel

NCBI

NCBI

WebMD